Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody (clone:OCA125/2

Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody (clone:OCA125/2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1216-20 20 µg -

3 - 11 business days*

287.00€
 
The mucins are a family of highly glycosylated, secreted proteins with a basic structure... more
Product information "Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody (clone:OCA125/2"
The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions. Protein function: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [The UniProt Consortium]
Keywords: Anti-MUC-16, Anti-CA-125, Anti-Mucin-16, Anti-Ovarian carcinoma antigen CA125, Anti-Ovarian cancer-related tumor marker CA125, Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:OCA125/2349R)
Supplier: Abeomics
Supplier-Nr: 12-1216-20

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: OCA125/2349R
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant full-length human MUC16 protein
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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