Anti-MRC1 (Macrophage Mannose Receptor 1, MMR, C-type Lectin Domain Family 13 Member D, C-type Lecti

MMR, also known as CD206 and MRC1, is a 175kD scavenger receptor that belongs to the C-type lectin protein family. MMR is expressed on tissue macrophages, myeloid dendritic cells, and liver and lymphatic endothelial cells. The extracellular region of MMR is composed of an N-terminal cysteine-rich domain, one fibronectin type II repeat, and eight C-type lectin carbohydrate recognition domains. MMR mediates the phagocytosis of sulfated N-acetylgalactosamine-containing molecules including those found on a variety of microorganisms. Within the extracellular region, mouse MMR shares 83% and 92% aa sequence identity with human and rat MMR. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Excitation: 488nm , Emission: 565-605nm, Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.