Product information "Anti-MLF1 Interacting Protein"
Protein function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression. [The UniProt Consortium]
Anti-CENPU, Anti-MLF1IP, Anti-CENP-U, Anti-CENP-50, Anti-Centromere protein U, Anti-MLF1-interacting protein, Anti-centromere protein of 50 kDa, Anti-Polo-box-interacting protein 1, Anti-Interphase centromere complex protein 24