Anti-MINK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-193A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-193A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Serine/threonine kinase which acts as a negative regulator of Ras-related... more

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Product information "Anti-MINK1"

Protein function: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. [The UniProt Consortium]

Keywords:	Anti-MEKKK 6, EC=2.7.11.1, Anti-MEK kinase kinase 6, Anti-GCK family kinase MiNK, Anti-Misshapen-like kinase 1, Anti-Misshapen/NIK-related kinase, Anti-MAPK/ERK kinase kinase kinase 6, Anti-Mitogen-activated protein kinase kinase kinase kinase 6
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-193A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: bovine, rabbit, pig, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, chinese hamster, small-eared galago, thirteen-lined ground squirrel, little brown bat, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-193A-T maps to a region between residue 775 and 825 of human misshapen-like kinase 1 using the numbering given in entry NP_722549.2 (GeneID 50488).
Format:	Antigen Affinity Purified