Anti-Melanoma gp100, clone NKI-beteb

Anti-Melanoma gp100, clone NKI-beteb
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2254SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. By immunohistochemistry, this melanoma gp100... more
Product information "Anti-Melanoma gp100, clone NKI-beteb"
1 mg/ml in sterile PBS, BSA free, sodium azide free. By immunohistochemistry, this melanoma gp100 antibody specifically recognizes a protein in melanocytes and melanomas. It reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. The melanoma gp100 antibody labels formalin/paraffin melanomas and other tumors showing melanocytic differentiation. Protein function: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [The UniProt Consortium]
Keywords: Anti-PMEL, Anti-D12S53E, Melanoma gp100 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2254SAF

Properties

Application: IHC, FC, IF
Antibody Type: Monoclonal
Clone: NKI-beteb
Conjugate: No
Host: Mouse
Species reactivity: human, horse
Immunogen: Membranes from a human melanoma metastasis were used as the immunogen for this Melanoma gp100 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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