Anti-MDM4 (Protein Mdm4, Double Minute 4 Protein, Mdm2-like p53-binding Protein, Protein Mdmx, p53-b

Anti-MDM4 (Protein Mdm4, Double Minute 4 Protein, Mdm2-like p53-binding Protein, Protein Mdmx, p53-b
Item number Size Datasheet Manual SDS Delivery time Quantity Price
H1827-70E.50 50 µl - -

1 - 19 business days

650.00€
 
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing... more
Product information "Anti-MDM4 (Protein Mdm4, Double Minute 4 Protein, Mdm2-like p53-binding Protein, Protein Mdmx, p53-b"
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:10,000, Western Blot: 1:500-1:2000, Immunohistochemistry: 1:200-1:1000, Immunohistochemistry (FFPE): 1:200 , Immunofluorescence: 1:200-1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: H1827-70E

Properties

Application: ELISA, IF, IHC, WB
Antibody Type: Monoclonal
Clone: 2D10F4
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant corresponding to human MDM4.
Format: Ascites

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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