Anti-MCM7

Anti-MCM7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-584A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A302-584A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative... more
Product information "Anti-MCM7"
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. [The UniProt Consortium]
Keywords: Anti-MCM7, Anti-CDC47, Anti-P1.1-MCM3, EC=3.6.4.12, Anti-CDC47 homolog, Anti-DNA replication licensing factor MCM7
Supplier: Bethyl Laboratories
Supplier-Nr: A302-584A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A302-584A-T maps to a region between residue 300 and 350 of human minichromosome maintenance deficient 7 using the numbering given in entry NP_005907.3 (GeneID 4176).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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