Anti-MBD3, NT (MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3) (Azide fr

Anti-MBD3, NT (MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3) (Azide fr
Item number Size Datasheet Manual SDS Delivery time Quantity Price
038234-HRP.200 200 µl - -

3 - 19 business days*

993.00€
 
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in... more
Product information "Anti-MBD3, NT (MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3) (Azide fr"
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-MBD3, Anti-Methyl-CpG-binding protein MBD3, Anti-Methyl-CpG-binding domain protein 3
Supplier: United States Biological
Supplier-Nr: 038234-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Species reactivity: human
Immunogen: MBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MBD3.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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