Anti-LTbetaR (mouse), clone 4H8 WH2 (preservative free)

Functional Application: Agonist inducing BAFF, chemokines and integrins in vitro and in vivo. The monoclonal antibody to mouse LTbetaR (preservative free) is an agonist that can be used for the investigation of the regulation of BAFF (BlyS), chemokines and integrins using in vivo and tissue culture models, the development of NK cells and NK T cells, to study the regulation of NF-kappaB family of transcription factors in regulation of inflammation and homeostasis, particularly RelB NF-?kappaB2 pathway. For use as an agonist the MAb to LTbetaR is added to cell cultures at 2 ?g/ml. For in vivo use, mice are injected intraperitoneally with 50 ?g of agonistic MAb to LTbetaR in sterile phosphate saline buffer.