Anti-LRWD1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-867A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-867A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition... more

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Product information "Anti-LRWD1"

Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. [The UniProt Consortium]

Keywords:	Anti-ORCA, Anti-LRWD1, Anti-CENP-33, Anti-Centromere protein 33, Anti-ORC-associated protein, Anti-Origin recognition complex-associated protein, Anti-Leucine-rich repeat and WD repeat-containing protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-867A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-867A-T maps to a region between residue 200 and 250 of human leucine-rich repeats and WD repeat domain containing 1 using the numbering given in entry NP_690852.1 (GeneID 222229).
Format:	Antigen Affinity Purified