Anti-LMNA, ID (LMNA, LMN1, Lamin-A/C, Lamin A, CDDC, CMD1A)

Anti-LMNA, ID (LMNA, LMN1, Lamin-A/C, Lamin A, CDDC, CMD1A)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
136228.50 50 µg - -

3 - 19 business days*

796.00€
 
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner... more
Product information "Anti-LMNA, ID (LMNA, LMN1, Lamin-A/C, Lamin A, CDDC, CMD1A)"
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in, evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:10,000, Western Blot: 1:500-1:1000, Immunohistochemistry (Paraffin): 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 136228

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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