Anti-LIME (Lck-interacting Transmembrane Adapter 1, Lck-interacting Molecule, Lime1)

Anti-LIME (Lck-interacting Transmembrane Adapter 1, Lck-interacting Molecule, Lime1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
L1566-06B.50 50 µg - -

1 - 19 business days

650.00€
 
LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation... more
Product information "Anti-LIME (Lck-interacting Transmembrane Adapter 1, Lck-interacting Molecule, Lime1)"
LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: L1566-06B

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant corresponding to aa141-295 of human LIME, bacterially expressed.
Format: Serum

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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