Anti-LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5, CD85 Antigen-like Family M

Anti-LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5, CD85 Antigen-like Family M
Item number Size Datasheet Manual SDS Delivery time Quantity Price
L2028-59.100 100 tests - -

3 - 19 business days*

636.00€
 
ILT11 is a 39-40kD Group 2 member of the LILR family of innate immune receptors. It is expressed... more
Product information "Anti-LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5, CD85 Antigen-like Family M"
ILT11 is a 39-40kD Group 2 member of the LILR family of innate immune receptors. It is expressed on monocytes and perhaps neutrophils, and its activation results in the secretion of pro-inflammatory cytokines, such as TNF-A and IL-1B. Mature human ILT11 is a 258aa type I transmembrane glycoprotein. It has a 227aa extracellular domain aa42-268 that contains two C2 type Ig-like domains aa51-136 and 142-230, and a 10aa cytoplasmic tail. ILT11 has three potential splice forms. One is a 35kD soluble form of the molecule described above that shows a 27aa substitution for aa239-299. The other two splice forms are analogous to the above membrane and soluble forms, but demonstrate signal sequence cleavage further downstream after Ala51. Over aa41-268, human ILT11 shares 58% aa identity with mouse LIR-9. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul to label 1x10e6 human peripheral blood monocytes, Optimal dilutions to be determined by the researcher. Excitation: 488nm , Emission: 565-605nm, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Keywords: Anti-CD85f, Anti-LIR-9, Anti-ILT11, Anti-LILRA5, Anti-ILT-11, Anti-Immunoglobulin-like transcript 11, Anti-CD85 antigen-like family member F, Anti-Leukocyte immunoglobulin-like receptor 9, Anti-Leukocyte immunoglobulin-like receptor subfamily A member 5
Supplier: United States Biological
Supplier-Nr: L2028-59

Properties

Application: FC
Antibody Type: Monoclonal
Clone: 12K126
Conjugate: Phycoerythrin
Host: Mouse
Reactivity: Human
Immunogen: Recombinant corresponding to human LILRA5 expressed in CHO cell line.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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