Anti-LGN

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-031A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-031A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Plays an important role in mitotic spindle pole organization via its... more

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Product information "Anti-LGN"

Protein function: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein- dynactin complex recruitment during metaphase (PubMed:22327364). Plays a role in metaphase spindle orientation (PubMed:22327364). Plays also an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity. [The UniProt Consortium]

Keywords:	Anti-LGN, Anti-GPSM2, Anti-Mosaic protein LGN, Anti-G-protein-signaling modulator 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-031A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, orangutan, chimpanzee, white-tufted-ear marmoset)
Immunogen:	synthetic peptide. The epitope recognized by A303-031A-T maps to a region between residue 450 and 500 of human Mosaic Protein LGN using the numbering given in entry AAH27732.1 (GeneID 29899).
Format:	Antigen Affinity Purified