Anti-LC3A, clone 166AT1234

Anti-LC3A, clone 166AT1234
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F40209-0.05ML 50 µl - -

3 - 10 business days*

326.00€
NSJ-F40209-0.2ML 200 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS pH 7.4 with 0.09% sodium azide. MAP1A and MAP1B are microtubule-associated proteins... more
Product information "Anti-LC3A, clone 166AT1234"
In 1X PBS pH 7.4 with 0.09% sodium azide. MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006538, PubMed:31006537). [The UniProt Consortium]
Keywords: Anti-MAP1LC3A, Anti-MAP1A/MAP1B LC3 A, Anti-MAP1A/MAP1B light chain 3 A, Anti-Autophagy-related protein LC3 A, Anti-MAP1 light chain 3-like protein 1, Anti-Autophagy-related ubiquitin-like modifier LC3 A, LC3A Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F40209

Properties

Application: WB
Antibody Type: Monoclonal
Clone: 166AT1234
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat
Immunogen: Full length recombinant protein of human LC3A/MAP1LC3A.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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