Anti-LBR (Lamin-B Receptor, Integral Nuclear Envelope Inner Membrane Protein, LMN2R)

Anti-LBR (Lamin-B Receptor, Integral Nuclear Envelope Inner Membrane Protein, LMN2R)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
L1220-40A.50 50 µg - -

1 - 19 business days

650.00€
 
Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as... more
Product information "Anti-LBR (Lamin-B Receptor, Integral Nuclear Envelope Inner Membrane Protein, LMN2R)"
Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 2.5-5ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: L1220-40A

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human
Immunogen: Synthetic peptide corresponding to C-KEIDSKEEKYVAK from aa178-190 of human LBR (NP_002287.2).
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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