Anti-Laminin beta1

Anti-Laminin beta1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-62812.60 60 µl - -

7 - 16 business days*

E-AB-62812.120 120 µl - -

7 - 16 business days*

E-AB-62812.200 200 µl - -

7 - 16 business days*

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous... more
Product information "Anti-Laminin beta1"
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have Protein function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. [The UniProt Consortium]
Keywords: Anti-LAMB1, Anti-Laminin B1 chain, Anti-Laminin subunit beta-1, Anti-Laminin-1 subunit beta, Anti-Laminin-8 subunit beta, Anti-Laminin-2 subunit beta, Anti-Laminin-6 subunit beta, Anti-Laminin-10 subunit beta, Anti-Laminin-12 subunit beta, Laminin beta1 P
Supplier: Elabscience
Supplier-Nr: E-AB-62812


Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human LAMB1

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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