Anti-Lactate Dehydrogenase A (L-lactate Dehydrogenase A Chain, LDHA, LDH-A, Cell Proliferation-induc

Anti-Lactate Dehydrogenase A (L-lactate Dehydrogenase A Chain, LDHA, LDH-A, Cell Proliferation-induc
Item number Size Datasheet Manual SDS Delivery time Quantity Price
L1011-10B.50 50 µl - -

1 - 19 business days

650.00€
 
Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and... more
Product information "Anti-Lactate Dehydrogenase A (L-lactate Dehydrogenase A Chain, LDHA, LDH-A, Cell Proliferation-induc"
Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: L1011-10B

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: 15j138
Conjugate: No
Host: Mouse
Reactivity: Human
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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