Anti-KCA3.1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-39-2053-100	100 µg		-		3 - 11 business days*		801.00€

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Intermediate conductance calcium-activated potassium channel protein 1(KCNN4, Kca3.1) is part of... more

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Product information "Anti-KCA3.1"

Intermediate conductance calcium-activated potassium channel protein 1(KCNN4, Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. Protein function: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614). [The UniProt Consortium]

Keywords:	Anti-SK4, Anti-IK1, Anti-KCa4, Anti-IKCa1, Anti-KCNN4, Anti-SKCa4, Anti-SKCa 4, Anti-KCa3.1, Anti-Putative Gardos channel, Anti-Intermediate conductance calcium-activated potassium channel protein 4, Polyclonal Antibody to Anti-KCA3.1 Antibody
Supplier:	Abeomics
Supplier-Nr:	39-2053

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	A synthetic peptide corresponding to a sequence at the N-terminal of human KCNN4(11-28aa ALRRRKRLLEQEKSLAGW), different from the related rat and mouse sequences by two amino acids.