Anti-Jumonji Domain Containing 2C (JMJD2C, JMJD2, Gene Amplified in Squamous Cell Carcinoma 1, GASC1

Anti-Jumonji Domain Containing 2C (JMJD2C, JMJD2, Gene Amplified in Squamous Cell Carcinoma 1, GASC1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
J7876-47.100 100 µl - -

3 - 19 business days

734.00€
 
Jumonji Domain Containing 2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a... more
Product information "Anti-Jumonji Domain Containing 2C (JMJD2C, JMJD2, Gene Amplified in Squamous Cell Carcinoma 1, GASC1"
Jumonji Domain Containing 2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Applications: Suitable for use in Western Blot, Chromatin Immunoprecipitation and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Western Blot: 1:2000-1:10,000, Immunoprecipitation: 1:2-5ug/mg lysate, Chromatin Immunoprecipitation: 1:10-1:500, Optimal dilutions to be determined by the researcher. Positive Control: HeLa whole cell extract, Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: J7876-47

Properties

Application: IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: The epitope recognized maps to a region between residue 475 and 525 of human Jumonji Domain Containing 2C using the numbering given in entry NP_055876.2 (GeneID 23081).
Purity: Purified by peptide immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: +4°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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