Anti-JARID1B

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-813A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A301-813A-M 100 µl (10 blots) -

3 - 9 business days

290.00€
A301-813A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a... more
Product information "Anti-JARID1B"
Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2. [The UniProt Consortium]
Keywords: Anti-CT31, Anti-PLU-1, Anti-KDM5B, Anti-JARID1B, Anti-RBP2-H1, EC=1.14.11.-, Anti-Cancer/testis antigen 31, Anti-Histone demethylase JARID1B, Anti-Lysine-specific demethylase 5B, Anti-Jumonji/ARID domain-containing protein 1B
Supplier-Nr: A301-813A-T

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse (Expected: Dog, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, African Elephant, Small-eared Galago, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-813A-T maps to a region between residue 1494 and 1544 of human Jumonji, AT rich interactive domain 1B using the numbering given in entry NP_006609.3 (GeneID 10765).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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