Anti-IRF2

Anti-IRF2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F41303-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F41303-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. IRF2 encodes interferon regulatory factor 2, a member... more
Product information "Anti-IRF2"
In 1X PBS, pH 7.4, with 0.09% sodium azide. IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq]. Protein function: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. [The UniProt Consortium]
Keywords: Anti-IRF2, Anti-IRF-2, Anti-Interferon regulatory factor 2, IRF2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F41303

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: A portion of amino acids 225-255 from the human protein was used as the immunogen for this IRF2 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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