Anti-IRAK2 (Interleukin-1 Receptor-associated Kinase-like 2, IRAK-2)

Anti-IRAK2 (Interleukin-1 Receptor-associated Kinase-like 2, IRAK-2)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
I8600-12E.50 50 µg - -

1 - 19 business days

774.00€
 
IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1... more
Product information "Anti-IRAK2 (Interleukin-1 Receptor-associated Kinase-like 2, IRAK-2)"
IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1 receptor (IL-1R) signaling cascade. IRAK2 also has been associated with signaling cell death, potentially via the Fas-associated death domain protein/caspase-8 apoptotic pathway. Dominant negative forms of IRAK2 attenuate IL-1R-mediated NF-kappa B activation, suggesting that IRAK-2 may serve as a therapeutic target for inhibiting IL-1-induced inflammation. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml, Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: I8600-12E

Properties

Application: ELISA, ICC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide corresponding to 17aa near the C-terminus of mouse IRAK2a which is common to all four isoforms conjugated to KLH.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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