Anti-IP3R1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-157A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-157A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Intracellular channel that mediates calcium release from the endoplasmic... more

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Product information "Anti-IP3R1"

Protein function: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. [The UniProt Consortium]

Keywords:	Anti-ITPR1, Anti-IP3R 1, Anti-INSP3R1, Anti-InsP3R1, Anti-Type 1 InsP3 receptor, Anti-IP3 receptor isoform 1, Anti-Inositol 1,4,5-trisphosphate receptor type 1, Anti-Type 1 inositol 1,4,5-trisphosphate receptor
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-157A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat, bovine)
Immunogen:	synthetic peptide. The epitope recognized by A302-157A-T maps to a region between residue 1025 and 1050 of human inositol 1,4,5-trisphosphate receptor type 1 using the numbering given in entry Q14643.2 (GeneID 3708).
Format:	Antigen Affinity Purified