Anti-INTS6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-61262.60 60 µl -

7 - 16 business days*

198.00€
E-AB-61262.120 120 µl -

7 - 16 business days*

317.00€
E-AB-61262.200 200 µl -

7 - 16 business days*

525.00€
 
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA... more
Product information "Anti-INTS6"
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. Protein function: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144). [The UniProt Consortium]
Keywords: Anti-Int6, Anti-DBI1, Anti-DBI-1, Anti-DICE1, Anti-INTS6, Anti-Protein DDX26, Anti-Protein deleted in cancer 1, Anti-Integrator complex subunit 6, INTS6 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-61262

Properties

Application: WB, IHC, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human INTS6

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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