Anti-Interleukin 27 (IL-27 (p28), Interleukin 17D, IL-17D, Interleukin 30, IL-30, MGC71873, p28)

Recently, a new heterodimeric cytokine termed IL-27 that consists of EBI3 (Epstein-Barr virus-induced gene 3), an IL-12p40-related protein, and p28, a newly discovered IL-12p35-related polypeptide has been discovered. IL-27 is involved in early Th1 initiation. Its action is mediated through the orphan cytokine receptor WSX-1/TCCR and gp130. IL-27 may also play a role in the induction of T-bet expression and regulation of Ig class switching in B cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.