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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay32218-100 | 100 µl | - |
6 - 10 business days* |
480.00€
|
Integrins are cell adhesion receptors that mediate the attachment of cells to the extracellular... more
Product information "Anti-Integrin alpha4/CD49D (C-Term) Rabbit"
Integrins are cell adhesion receptors that mediate the attachment of cells to the extracellular matrix (ECM) and facilitate cell-cell interactions. The integrin family contains 18 alpha subunits and eight beta subunits that form 24 different heterodimers grouped into familial subgroups based on subunit composition and/or their ligand binding properties. Integrin alpha4, also known as CD49D, is a subunit of the alpha4beta1 and alpha4beta7 leukocyte-specific integrins, which recognize fibronectin and vascular cell adhesion molecule 1 (VCAM-1) and have essential roles in lymphocyte migration. Knockout of Itga4, the gene encoding integrin alpha4, induces failure of chorioallantoic fusion and is embryonic lethal in mice. Cayman's Integrin alpha4/CD49D (C-Term) Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.Synonyms: CD49D, Integrin Subunit alpha4, Very Late Activation Protein 4 Receptor, alpha4 subunit, VLA-4 subunit alpha, Integrin alphaIV. Immunogen: Peptide from the C-terminal region of human integrin alpha4. Clone Designation: RM268. Formulation: (Request formulation change), 100 µl of protein A-affinity purified monoclonal antibody. Storage Buffer: PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Host: Rabbit. Isotype: IgG. Applications: IHC, WB. Cross Reactivity: (+) Integrin alpha4.
Keywords: | CD49D, Integrin Subunit alpha4, Integrin alphaIV, Very Late Activation Protein 4 Receptor, alpha4 subunit, VLA-4 subunit alpha |
Supplier: | Cayman Chemical |
Supplier-Nr: | 32218 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | RM268 |
Conjugate: | No |
Host: | Rabbit |
Immunogen: | Peptide from the C-terminal region of human integrin ?4 |
Format: | Purified |
Database Information
KEGG ID : | K06483 | Matching products |
UniProt ID : | P13612 | Matching products |
Gene ID | GeneID 3676 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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