Anti-Integrin alpha 1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-39-2051-100 100 µg -

3 - 11 business days*

801.00€
 
Integrin alpha 1(ITGA1) chain associates with the beta 1(ITGB1) chain to form a heterodimer that... more
Product information "Anti-Integrin alpha 1"
Integrin alpha 1(ITGA1) chain associates with the beta 1(ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MHC proliferation and cartilage production. Protein function: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. [The UniProt Consortium]
Keywords: Anti-CD49a, Anti-ITGA1, Anti-VLA-1, Anti-Integrin alpha-1, Anti-Laminin and collagen receptor, Anti-CD49 antigen-like family member A, Polyclonal Antibody to Anti-Integrin alpha 1 Antibody
Supplier: Abeomics
Supplier-Nr: 39-2051

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of Human Integrin alpha 1(43-60aa VEDMFGYTVQQYENEEGK), identical to the related Rat and Mouse sequences.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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