Protein function: Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. [The UniProt Consortium]
Anti-Int11, Anti-RC-68, Anti-CPSF3L, Anti-INTS11, EC=3.1.27.-, Anti-CPSF3-like protein, Anti-Integrator complex subunit 11, Anti-Protein related to CPSF subunits of 68 kDa, Anti-Cleavage and polyadenylation-specific factor 3-like protein
synthetic peptide. The epitope recognized by A301-274A-T maps to a region between residue 550 and 600 of human integrator complex subunit 11 using the numbering given in entry NP_060341.2 (GeneID 54973).