Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-661A-T 20 µl (2 blots) -

3 - 9 business days*

A302-661A-M 100 µl (10 blots) -

3 - 9 business days*

A302-661A 100 µl (100 µg) -

3 - 9 business days*

Protein function: Translational regulator that ensures constant high levels of translation upon a... more
Product information "Anti-IMPACT"
Protein function: Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity, impairs GCN1- mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth. [The UniProt Consortium]
Keywords: Anti-IMPACT, Anti-Protein IMPACT, Anti-Imprinted and ancient gene protein homolog
Supplier: Bethyl Laboratories
Supplier-Nr: A302-661A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-661A-T maps to a region between residue 270 and 320 of human imprinted and ancient homolog using the numbering given in entry NP_060909.1 (GeneID 55364).
Format: Antigen Affinity Purified

Database Information

UniProt ID : Q9P2X3 | Find alternatives
Gene ID GeneID 55364 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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