Anti-IL24

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-17913.20 20 µl -

7 - 16 business days*

71.00€
E-AB-17913.60 60 µl -

7 - 16 business days*

143.00€
E-AB-17913.120 120 µl -

7 - 16 business days*

238.00€
E-AB-17913.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced... more
Product information "Anti-IL24"
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.IL24 (Interleukin 24) is a Protein Coding gene. Diseases associated with IL24 include Melanoma and Subclavian Steal Syndrome. Among its related pathways are PEDF Induced Signaling and Immune response IL-23 signaling pathway. GO annotations related to this gene include cytokine activity. An important paralog of this gene is IL20. Protein function: Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation. [The UniProt Consortium]
Keywords: Anti-IL24, Anti-MDA7, Anti-MDA-7, Anti-IL-24, Anti-Interleukin-24, Anti-Suppression of tumorigenicity 16 protein, Anti-Melanoma differentiation-associated gene 7 protein, IL24 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-17913

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide of human IL24

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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