Anti-IL23 p19

Anti-IL23 p19
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R30542 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin-23 is a heterodimeric cytokine... more
Product information "Anti-IL23 p19"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. The cytokine is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration. Protein function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. [The UniProt Consortium]
Keywords: Anti-Il23a, Anti-IL-23-A, Anti-IL-23p19, Anti-IL-23 subunit alpha, Anti-Interleukin-23 subunit p19, Anti-Interleukin-23 subunit alpha, IL23 p19 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R30542

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse
Immunogen: An amino acid sequence from the N-terminus of mouse IL23 p19 (DWAQCQQLSRNLCMLAWNAH) was used as the immunogen for this IL23 p19 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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