Anti-IL1RAP (human), Unconjugated Clone B-L43

Anti-IL1RAP (human), Unconjugated Clone B-L43
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DC-857.093.020 200 tests (2 ml) -

3 - 8 business days*

157.00€
 
Specificity: Recognizes natural and recombinant human IL1RAP, Format: Phosphate-buffered saline... more
Product information "Anti-IL1RAP (human), Unconjugated Clone B-L43"
Specificity: Recognizes natural and recombinant human IL1RAP, Format: Phosphate-buffered saline with 1% BSA and 0.09% sodium azide, Working Dilution: Use 10 µl to label 106 cells or 100 µl of whole blood, Storage: Stable at +2-8°C for 12 months. For longer storage freeze aliquots. Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD. May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (Probable). [The UniProt Consortium]
Keywords: Anti-IL1RAP, Anti-IL-1R3, Anti-C3orf13, Anti-IL-1R-3, Anti-IL-1RAcP, Anti-Interleukin-1 receptor 3, Anti-IL-1 receptor accessory protein, Anti-Interleukin-1 receptor accessory protein, Anti-Human IL1RAP Monoclonal Antibody, Unconjugated Clone B-L43
Supplier: Diaclone
Supplier-Nr: 857.093

Properties

Application: FC
Antibody Type: Monoclonal
Clone: B-L43
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human IL1RAP

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: °C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H310, H410, EUH032
P Phrases: P262, P264, P270, P273, P280, P321, P330, P391, P301+P310, P302+P352, P361+P364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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