Anti-IL-33 (mouse)

Anti-IL-33 (mouse)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-25A-0047-C100 100 µg -

3 - 9 business days*

10 %
341.00€
306.90€
 
Recognizes mouse IL-33. Detects a band of about 18kDa by Western blot. Does not cross-react with... more
Product information "Anti-IL-33 (mouse)"
Recognizes mouse IL-33. Detects a band of about 18kDa by Western blot. Does not cross-react with human IL-33. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
Keywords: Interleukin-33, IL-1F11, NF-HEV
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-25A-0047

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse
Immunogen: Recombinant mouse IL-33.
MW: 18 kD
Format: Purified

Database Information

KEGG ID : K12967 | Matching products
UniProt ID : Q8BVZ5 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-IL-33 (mouse)"
Write a review
or to review a product.
Viewed