Anti-IL-1RAcP

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-BV3 100 µg - -

6 - 10 business days*

684.00€
 
Anti-IL-1RAcP Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-IL-1RAcP"
Anti-IL-1RAcP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. It has no cross activity to other member in the IL-1 receptor family. Protein function: Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1- dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non- signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand- bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. [The UniProt Consortium]
Keywords: Anti-IL1RAP, Anti-IL-1R3, Anti-IL-1R-3, Anti-C3orf13, Anti-IL-1RAcP, Anti-Interleukin-1 receptor 3, Anti-IL-1 receptor accessory protein, Anti-Interleukin-1 receptor accessory protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-BV3

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Peptide corresponding to amino acids near the C-terminus of IL-1RAcP, which differs from. The sequence of mouse origin by three amino acids.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-IL-1RAcP"
Write a review
or to review a product.
Viewed