Anti-IKZF1 / Ikaros (PE), clone 4E9

Anti-IKZF1 / Ikaros (PE), clone 4E9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG42282.50 50 tests - -

6 - 14 business days*

520.00€
 
Protein function: Transcription regulator of hematopoietic cell differentiation... more
Product information "Anti-IKZF1 / Ikaros (PE), clone 4E9"
Protein function: Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067). [The UniProt Consortium]
Keywords: Anti-IK1, Anti-IKZF1, Anti-DNA-binding protein Ikaros, Anti-Ikaros family zinc finger protein 1, Anti-Lymphoid transcription factor LyF-1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG42282

Properties

Application: FC
Antibody Type: Monoclonal
Clone: 4E9
Conjugate: Phycoerythrin
Host: Mouse
Species reactivity: human, mouse
Immunogen: Recombinant Human Ikaros (C-terminal part)
MW: 58 kD
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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