Anti-IKKgamma

Anti-IKKgamma
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-25T-0010-C100 100 µg -

3 - 9 business days*

286.00€
 
Recognizes human and mouse IKK-gamma. Protein function: Regulatory subunit of the IKK core... more
Product information "Anti-IKKgamma"
Recognizes human and mouse IKK-gamma. Protein function: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'- linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B- mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response, this function requires 'Lys-27'-linked polyubiquitination. [The UniProt Consortium]
Keywords: Anti-IKKG, Anti-FIP3, Anti-NEMO, Anti-FIP-3, Anti-IKBKG, Anti-IKKAP1, Anti-IKK-gamma, Anti-IkB kinase subunit gamma, Anti-NF-kappa-B essential modifier, Anti-NF-kappa-B essential modulator, Anti-I-kappa-B kinase subunit gamma
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-25T-0010

Properties

Application: ELISA, IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Recombinant human IKK-gamma (aa 40-210).
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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