Anti-ID2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-16502.20 20 µl -

7 - 16 business days*

71.00€
E-AB-16502.60 60 µl -

7 - 16 business days*

143.00€
E-AB-16502.120 120 µl -

7 - 16 business days*

238.00€
E-AB-16502.200 200 µl -

7 - 16 business days*

396.00€
 
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which... more
Product information "Anti-ID2"
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. Protein function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism. [The UniProt Consortium]
Keywords: Anti-ID2, Anti-bHLHb26, Anti-BHLHB26, Anti-Inhibitor of DNA binding 2, Anti-Inhibitor of differentiation 2, Anti-DNA-binding protein inhibitor ID-2, Anti-Class B basic helix-loop-helix protein 26, ID2 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-16502

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human ID2
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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