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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
I0650-01A1.100 | 100 µg | - | - |
3 - 19 business days* |
621.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The inducible costimulator CD278 (ICOS, T cell activation molecule H4) is similar to human CD28... more
Product information "Anti-ICOS (Inducible T-cell Costimulator, Inducible T-cell Co-stimulator, Activation-inducible Lymph"
The inducible costimulator CD278 (ICOS, T cell activation molecule H4) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or ICOS results in discrete cytokine secretion profiles by the activated T cells (1). Signaling by either molecule is effectively down regulated by CD152 (CTLA-4) engagement (2). Human GL50 is a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2), and has been shown to be the ligand for ICOS. Two RNA splice variants exist for this molecule, differing only in the cytoplasmic domain (4). Applications: Suitable for use in ELISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | I0650-01A1 |
Properties
Application: | ELISA, FC |
Antibody Type: | Monoclonal |
Clone: | 7H152 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human HPB-MLT cells, ICOS-muIg fusion protein |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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