Anti-ICOS

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-67295.60 60 µl -

7 - 16 business days*

198.00€
E-AB-67295.120 120 µl -

7 - 16 business days*

317.00€
E-AB-67295.200 200 µl -

7 - 16 business days*

525.00€
 
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It... more
Product information "Anti-ICOS"
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin- 2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40- mediated class switching of immunoglobin isotypes. [The UniProt Consortium]
Keywords: Anti-ICOS, Anti-CD278, Anti-AILIM, Anti-Inducible T-cell costimulator, Anti-Activation-inducible lymphocyte immunomediatory molecule, ICOS Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-67295

Properties

Application: IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant fusion protein of human ICOS (NP_036224.1).

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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