Anti-Human Papilloma Virus Type 16 (HPV)

Anti-Human Papilloma Virus Type 16 (HPV)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P3105-07A.1 1 mg - -

3 - 19 business days*

734.00€
 
Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous... more
Product information "Anti-Human Papilloma Virus Type 16 (HPV)"
Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupt normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-supressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Recommended Pair: Suitable for use as the capture or solid phase antibody., Matched to P3105-16D, P3105-16F or P3105-25C as the detection or conjugate (label) antibody. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: P3105-07A

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 9B102
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: HPV oncoprotein E7, type 16.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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