Anti-Human CD32 NALE(TM) Purified (Clone: 6C4)

Anti-Human CD32 NALE(TM) Purified (Clone: 6C4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-43-1022-100 100 µg -

3 - 11 business days*

374.00€
 
The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and... more
Product information "Anti-Human CD32 NALE(TM) Purified (Clone: 6C4)"
The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDa polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding Protein function: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. [The UniProt Consortium]
Keywords: Anti-CD32, Anti-CDw32, Anti-FCGR2B, Anti-FcRII-b, Anti-Fc-gamma-RIIb, Anti-Fc-gamma RII-b, Anti-IgG Fc receptor II-b, Anti-Low affinity immunoglobulin gamma Fc region receptor II-b, Monoclonal Antibody to Human CD32 NALE(TM) Purified (Clone: 6C4)
Supplier: Abeomics
Supplier-Nr: 43-1022

Properties

Application: FA
Antibody Type: Monoclonal
Clone: 6C4
Conjugate: No
Host: Mouse
Reactivity: Human
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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