Anti-hPD-L1 (Clone: ABM4E54) (NALE(TM) No Azide Low Endotoxin)

Anti-hPD-L1 (Clone: ABM4E54) (NALE(TM) No Azide Low Endotoxin)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-10-7562-NALE-100 100 µg - -

2 - 11 business days

359.00€
 
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7... more
Product information "Anti-hPD-L1 (Clone: ABM4E54) (NALE(TM) No Azide Low Endotoxin)"
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases. Protein function: Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. [The UniProt Consortium]
Keywords: Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1, NALE Monoclonal Antibody to hPD-L1 (Clone: ABM4E54) (No Azide Low Endotoxin)
Supplier: Abeomics
Supplier-Nr: 10-7562-NALE

Properties

Application: FC, IHC, WB
Antibody Type: Monoclonal
Clone: ABM4E54
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A partial length recombinant PDL1 protein (amino acids 18-227) was used as the immunogen for this antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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