Anti-HMGB1 (Clone IMG19N10B7)

Anti-HMGB1 (Clone IMG19N10B7)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11512-1 1 each -

6 - 10 business days*

440.00€
 
High Mobility Group Protein B1 (HMGB1) belongs to the HMGB family and contains two HMG box... more
Product information "Anti-HMGB1 (Clone IMG19N10B7)"
High Mobility Group Protein B1 (HMGB1) belongs to the HMGB family and contains two HMG box DNA-binding domains. It is a highly conserved, ubiquitous protein present in the nuclei and cytoplasm of nearly all cell types, and is a necessary and sufficient mediator of inflammation during sterile and infection-associated responses. HMGB1 also act as DNA nuclear binding protein that has recently been shown to be an early trigger of sterile inflammation in animal models of trauma-hemorrhage via the activation of the Toll-like receptor 4 (TLR4) and the receptor for the advanced glycation endproducts (RAGE). It is reported that the level of HMGB1 is elevated during sterile tissue injury, infection, lethal endotoxemia or sepsis, collagen-induced arthritis, and ischemia-reperfusion induced tissue injury.Synonyms: High Mobility Group Protein B1, HMG1. Immunogen: full length recombinant human HMGB1. Clone Designation: IMG19N10B7. Formulation: (Request formulation change), 100 µg of Protein G purified IgG2bk in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Host: Mouse. Isotype: IgG2bkappa. Applications: FC, IHC (paraffin-embedded tissue), and WB.
Keywords: High Mobility Group Protein B1, HMG1
Supplier: Cayman Chemical
Supplier-Nr: 11512

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: IMG19N10B7
Conjugate: No
Host: Mouse
Species reactivity: human, mouse
Immunogen: full length recombinant human HMGB1
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-HMGB1 (Clone IMG19N10B7)"
Write a review
or to review a product.
Viewed