Anti-Histone H3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-67434.60 60 µl -

7 - 16 business days*

198.00€
E-AB-67434.120 120 µl -

7 - 16 business days*

317.00€
E-AB-67434.200 200 µl -

7 - 16 business days*

525.00€
 
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the... more
Product information "Anti-Histone H3"
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
Keywords: Anti-H3t, Anti-H3/g, Anti-H3/t, Anti-H3FT, Anti-Histone H3.4, Anti-Histone H3.1t, Histone H3 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-67434

Properties

Application: WB, IHC, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: A synthetic peptide of human HIST3H3 (NP_003484.1).

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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