Anti-HIP1/Huntingtin-interacting Protein 1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-175A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A305-175A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990,... more

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Product information "Anti-HIP1/Huntingtin-interacting Protein 1"

Protein function: Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)-mediated transcription (PubMed:16027218). May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801). Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715). May play a functional role in the cell filament networks (PubMed:18790740). May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454). [The UniProt Consortium]

Keywords:	Anti-HIP1, Anti-HIP-1, Anti-HIP-I, Anti-Huntingtin-interacting protein I, Anti-Huntingtin-interacting protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-175A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, gorilla, chimpanzee, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A305-175A-T maps to a region between residue 725 to 775 of human Huntingtin-interacting protein 1 using the numbering given in entry O00291.5 (GeneID 3092).
Format:	Antigen Affinity Purified