Anti-HGF (HGF, HPTA, Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, Hepatocyte growth fa

Anti-HGF (HGF, HPTA, Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, Hepatocyte growth fa
Item number Size Datasheet Manual SDS Delivery time Quantity Price
031014-AP.200 200 µl - -

3 - 19 business days*

731.00€
 
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a... more
Product information "Anti-HGF (HGF, HPTA, Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, Hepatocyte growth fa"
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100~250, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with the addition of glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive., , Note: Applications are based on unconjugated antibody.
Supplier: United States Biological
Supplier-Nr: 031014-AP

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 489CT6.12.6
Conjugate: No
Host: Mouse
Reactivity: Human
Format: Affinity Purified

Database Information

UniProt ID : P14210 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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