Anti-HES1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-F49550-0.08ML 80 µl - -

3 - 10 business days*

326.00€
NSJ-F49550-0.4ML 400 µl - -

3 - 10 business days*

702.00€
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. HES1 belongs to the basic helix-loop-helix family of... more
Product information "Anti-HES1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES1 has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. Protein function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. [The UniProt Consortium]
Keywords: Anti-hHL, Anti-HES1, Anti-bHLHb39, Anti-BHLHB39, Anti-Hairy homolog, Anti-Hairy-like protein, Anti-Transcription factor HES-1, Anti-Hairy and enhancer of split 1, Anti-Class B basic helix-loop-helix protein 39, HES1 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: F49550

Properties

Application: FC, WB, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A portion of amino acids 9-38 from the human protein was used as the immunogen for this HES1 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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