Anti-HES1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55547.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Transcriptional repressor of genes that require a bHLH protein for their... more

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Product information "Anti-HES1"

Protein function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. [The UniProt Consortium]

Keywords:	Anti-hHL, Anti-HES1, Anti-bHLHb39, Anti-BHLHB39, Anti-Hairy homolog, Anti-Hairy-like protein, Anti-Transcription factor HES-1, Anti-Hairy and enhancer of split 1, Anti-Class B basic helix-loop-helix protein 39
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55547

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 259-293 (C-terminus) of Human HES1
Format:	Purified