Anti-HERPUD1, NT (HERPUD1, HERP, KIAA0025, MIF1, Homocysteine-responsive endoplasmic reticulum-resid

Anti-HERPUD1, NT (HERPUD1, HERP, KIAA0025, MIF1, Homocysteine-responsive endoplasmic reticulum-resid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036516-FITC.200 200 µl - -

3 - 19 business days*

993.00€
 
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress... more
Product information "Anti-HERPUD1, NT (HERPUD1, HERP, KIAA0025, MIF1, Homocysteine-responsive endoplasmic reticulum-resid"
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq]. Applications: Suitable for use in Western Blot and FLISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-HERP, Anti-HERPUD1, Anti-Methyl methanesulfonate (MMF)-inducible fragment protein 1, Anti-Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Supplier: United States Biological
Supplier-Nr: 036516-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Species reactivity: human
Immunogen: HERPUD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human HERPUD1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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